The development of advanced optical imaging techniques for in vivo imaging of biological tissues is currently underway by the team at NTU Optical Bio-Imaging Centre (NOBIC).
One of the projects involves the construction and validation of custom 2-photon microscopes capable of performing simultaneous 2-photon imaging and 2-photon optogenetics of neurons in small animals. These microscopes are highly optimized and customizable to meet the demands of neuroscience research at NTU LKC Medicine.

Upcoming plans include incorporating adaptive optics to further enhance the capability of the 2-photon microscopes to preserve spatial resolution when imaging through highly-scattering biological tissues.
Watch this space for more updates!
Credits: https://www.nobic.sg/Projects.html#2-phot
Team: Josiah CHONG, Peter TÖRÖK, Aalim KHAN, Louwrens van DELLEN, Sean KRUPP, Nicholas MOK, Sayyed Omar Kamal