Long-range formation of the Bicoid gradient requires multiple dynamic modes that spatially vary across the embryo

This study looked at how a protein called Bicoid (Bcd) forms a gradient in fruit fly embryos, which is essential for the embryo to develop correctly.  It was found that Bcd moves differently in different parts of the embryo, moving faster at one end.  This difference in movement helps to create the Bcd gradient, which is important for determining the head-to-tail development of the embryo.

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¹Warwick Medical School, University of Warwick, United Kingdom. ²Mechanobiology Institute, National University of Singapore, Singapore. ³Department of Biological Sciences and Centre for Bioimaging Sciences, National University of Singapore, Singapore. ⁴Cornell University, USA. ⁵Kennedy Institute of Rheumatology, University of Oxford, UK. ⁶Department of Chemistry, National University of Singapore.